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Exploring the zero operator access design of Mantle

At Amazon, our culture, built on honest and transparent discussion of our growth opportunities, enables us to focus on investing and innovating to continually raise the standard on our ability to deliver value for our customers. Earlier this month, we had the opportunity to share an example of this process at work in Mantle, our …

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Move Beyond Chain-of-Thought with Chain-of-Draft on Amazon Bedrock

As organizations scale their generative AI implementations, the critical challenge of balancing quality, cost, and latency becomes increasingly complex. With inference costs dominating 70–90% of large language model (LLM) operational expenses, and verbose prompting strategies inflating token volume by 3–5x, organizations are actively seeking more efficient approaches to model interaction. Traditional prompting methods, while effective, …

A new tool is revealing the invisible networks inside cancer

Spanish researchers have created a powerful new open-source tool that helps uncover the hidden genetic networks driving cancer. Called RNACOREX, the software can analyze thousands of molecular interactions at once, revealing how genes communicate inside tumors and how those signals relate to patient survival. Tested across 13 different cancer types using international data, the tool …

BED-LLM: Intelligent Information Gathering with LLMs and Bayesian Experimental Design

We propose a general-purpose approach for improving the ability of Large Language Models (LLMs) to intelligently and adaptively gather information from a user or other external source using the framework of sequential Bayesian experimental design (BED). This enables LLMs to act as effective multi-turn conversational agents and interactively interface with external environments. Our approach, which …

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A New Era of Defense Innovation

Leading the Charge on Procurement Reform America’s defense industrial base stands on the precipice of massive, historic change. Given its access to a flourishing and dynamic private sector, the US defense industrial base should be a nimble, powerful engine of both creativity and lethality, capable of churning out the kinds of innovations that guarantee dominance …

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Introducing SOCI indexing for Amazon SageMaker Studio: Faster container startup times for AI/ML workloads

Today, we are excited to introduce a new feature for SageMaker Studio: SOCI (Seekable Open Container Initiative) indexing. SOCI supports lazy loading of container images, where only the necessary parts of an image are downloaded initially rather than the entire container. SageMaker Studio serves as a web Integrated Development Environment (IDE) for end-to-end machine learning (ML) development, …

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Cloud CISO Perspectives: 2025 in review: Cloud security basics and evolving AI

Welcome to the second Cloud CISO Perspectives for December 2025. Today, Google Cloud’s Nick Godfrey, senior director, and Anton Chuvakin, security advisor, look back at the year that was. As with all Cloud CISO Perspectives, the contents of this newsletter are posted to the Google Cloud blog. If you’re reading this on the website and …

Korrektur: Wie das Online-Magazin Die Republik einen Regierungsbericht zu Palantir verdrehte

(Scroll down for English translation below) Einleitung In einem im Dezember 2025 erschienenen Artikel des Magazins Republik wird auf einen Bericht des Armeestabs der Schweizer Armee aus dem Jahr 2024 aufmerksam gemacht, in dem eine mögliche Einführung der Software unseres Unternehmens Palantir Technologies Inc. (Palantir) bewertet wird. Der Artikel zeichnet ein falsches wie irreführendes Bild …

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Build and deploy scalable AI agents with NVIDIA NeMo, Amazon Bedrock AgentCore, and Strands Agents

This post is co-written with Ranjit Rajan, Abdullahi Olaoye, and Abhishek Sawarkar from NVIDIA. AI’s next frontier isn’t merely smarter chat-based assistants, it’s autonomous agents that reason, plan, and execute across entire systems. But to accomplish this, enterprise developers need to move from prototypes to production-ready AI agents that scale securely. This challenge grows as …